Test Code 5NTDSO 5'-Nucleotidase, Serum
Additional Codes
Mayo Test Code: 5NTD
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Useful For
Aiding diagnosis and monitoring of hepatobiliary disease and bile duct obstructions
Ruling out bone pathology as the source of elevated serum alkaline phosphatase
Method Name
Coupled Enzyme Kinetic Assay
Reporting Name
5'-Nucleotidase, SSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 90 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
<4.6 U/L
For International System of Units (SI) conversion for Reference Values, see www.mayocliniclabs.com/order-tests/si-unit-conversion.html.
Cautions
Alkaline phosphatase (ALP) is known to cross-react with 5'-nucleotidase (5'NT) measurements. Placental ALP of 100 U/L gives a 5'NT result of 0.27 U/L. Accordingly, specimens with elevations of any ALP isoenzyme significantly above normal circulating activity must be interpreted cautiously.
5'-nucleotidase is neither specific nor sensitive enough to be used as a cancer screen.
Do not interpret serum 5' NT activity as absolute evidence of the presence or the absence of malignant disease. Use serum 5' NT in conjunction with information from the clinical evaluation of the patient and other diagnostic procedures.
Values obtained with different assay methods or kits may be different and cannot be used interchangeably.
Day(s) Performed
Monday through Saturday
Report Available
1 to 3 daysSpecimen Retention Time
2 weeksPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83915
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| 5NTD | 5'-Nucleotidase, S | 1690-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 5NTD | 5'-Nucleotidase, S | 1690-7 |