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HelpTest Code ACELPAN Celiac Panel, Age over 2 years
Useful For
Order ACELPAN (Celiac Panel, Age over 2 years) on patients who HAVE reached their 3rd birthday. If the patient HAS NOT reached their 3rd birthday, order PCELPAN (Celiac Panel, Age 2 and under).
An initial serological assessment for suspected celiac disease. Panel includes tissue transglutaminase (tTG) IgA antibody, and a serum IgA level. If serum IgA levels are low, reflexive testing for tTG IgG antibody, and deamidated gliadin peptide (DGP) IgG antibody will be performed at an additional charge.
Synonyms/Keywords
Sprue, Celiac, tTG
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 1.0 mL | 1.0 mL | 0.5 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
| Gross lipemia |
|---|
| Gross hemolysis |
| Heat inactivated samples |
Test Components
Serum IgA level
Tissue Transglutaminase (tTG) IgA
Test Information
Panel includes tTG-IgA, and total serum IgA. Patients with celiac disease produce tTG antibodies of the IgA isotype. Low levels of serum IgA may indicate an impaired production of IgA antibodies. When low serum IgA levels are detected, tTG IgG and DGP IgG will be reflex ordered at an additional charge. Tissue transglutaminase IgG and gliadin IgG antibody tests provide additional support for a differential diagnosis.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | tTG-IgA: Negative <15 U/mL |
| tTG-IgG: Negative <15 U/mL | |
| Gliadin IgG: Negative <15 U/mL | |
| Serum IgA: See "Immunoglobulin A" test for age specific ranges |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Flow Immunoassay/ BioRad Bioplex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86364 | 1 | tTG IgA | ||
| 82784 | 1 | Serum IgA | ||
| 86258 | 1 | Gliadin IgG Antibodies | If Reflexed | |
| 86364 | 1 | tTG IgG | If Reflexed |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86364 | 1 | tTG IgA | ||
| 82784 | 1 | Serum IgA | ||
| 86258 | 1 | Gliadin IgG Antibodies | If Reflexed | |
| 86364 | 1 | tTG IgG Antibodies | If Reflexed |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Celiac Panel, age over 2 years |