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Test Code ACETA Acetaminophen

Useful For

Acetaminophen is an analgesic, antipyretic drug.  It rarely requires therapeutic monitoring, but is frequently found in overdose cases, particularly accidental ingestion in children.  With large doses, liver toxicity can result. 


Levels most accurately predict toxicity when sample is drawn between 4 and 12 hours after ingestion. Samples drawn less than 4 hours after ingestion may be misleading, as the peak concentration has not been reached.

Synonyms/Keywords

Datril, Tylenol

Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No Plasma/Serum Lithium-heparin Plasma Separator Tube (PST)

Serum Separator Tube (SST)

 

Red Top Tube (RTT)

 

Lithium or Sodium-heparin Green Top Tube (GTT)   EDTA Lavender Top Tube (LTT)

0.5 mL 0.3 mL  

Collection/Processing Instructions

Serum/Plasma must be separated from cells within 2 hours of collection.

Specimen Stability Information

Specimen Type Temperature Time
Serum/Plasma Ambient 8 hours
Refrigerate 7 days
Frozen >7 days

Interpretations

Liver damage is likely if >50 ug/mL at 12 hours or >200 ug/mL at 4 hours.

Reference Range Information

Performing Location Reference Range
All Performing Sites

Therapeutic Range: <10 ug/mL
Non-toxic: <50 ug/mL at 12 hours post-ingestion.

See Critical Value List for list of current critical values

Marshfield Labs Performing Department

Marshfield Labs Chemistry

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Beaver Dam Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU
Weston Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU
Eau Claire Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU
Park Falls Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU 
Ladysmith  Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU
Rice Lake Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU
Marshfield Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU
Minocqua Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU
Neillsville Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU
Stevens Point Monday through Sunday Less than 2 hours Emit* Tox Rate Assay/Beckman AU

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
80143   1    

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
80143   1    

Ordering Applications

Ordering Application Description
Cerner Acetaminophen Level