Test Code ACTH-P Adrenocorticotropic Hormone (ACTH)
Useful For
This test is useful for determining the cause of hypercortisolism and hypocortisolism states.
Synonyms/Keywords
ACTH, Corticotropin
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Plasma | EDTA Pink Top Tube (PTT)-pre-chilled | EDTA Lavender Top Tube (LTT)-pre-chilled | 0.5 mL | 0.5 mL | 0.4 mL |
Collection/Processing Instructions
1. Morning (6 a.m.-10:30 a.m.) specimen is desirable.
2. Collect with a pre-chilled pink or lavender top (EDTA) tube and transport to the laboratory on ice.
3. Centrifuge at refrigerated temperature within 2 hours and immediately separate plasma from cells.
4. If sample is received on off-hours", immediately freeze plasma. If during normal business hours (M-F, 8am 3pm), deliver to department on wet ice.
For outreach clients without a refrigerated centrifuge: Please deliver to Marshfield Labs within 2 hours of collection in a chilled tube, transported on ice. Or schedule the patient to be drawn at a location with a refrigerated centrifuge.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma | Refrigerated | 12 hours |
| Frozen | 30 days |
Rejection Criteria
Specimens refrigerated greater than 12 hours
Test Information
Morning (6 a.m. to 10 a.m.) specimens are desirable. This test is useful for determining the cause of hypercortisolism and hypocortisolism states.
The drug asfotase alfa (STRENSIQ), a recombinant form of alkaline phosphatase, is expected to interfere with in vitro diagnostic assays utilizing an alkaline phosphatase detection system. Test samples from patients taking asfotase alfa with a non-alkaline phosphatase methodology.
Interpretations
Lower level of reporting is 5 pg/mL. No established reference ranges for p.m. draws.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | 0 - 46 pg/mL (a.m. draws). |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | DPC Immulite |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82024 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82024 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | ACTH |