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HelpTest Code APTTH Heparin Neutralization - APTT
Useful For
Hepzyme neutralization of plasma to rule out presence of heparin, typically to rule out possible line contamination with heparin.
Synonyms/Keywords
Hepasorb Correction
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Whole Blood, Plasma | 3.2% Sodium Citrate Blue Top Tube (BTT) | 1.5 mL plasma | 1.0 mL plasma | 0.8 mL plasma |
Collection/Processing Instructions
- Citrated Blue Top Tube (BTT) must be drawn to the fill line.
- Completely invert tube three or four times to mix. Do Not Shake.
- Centrifuge tube at 3000 rpm for 10 minutes or Stat Spin for 3 minutes at 8500 rpm with the brake OFF as soon as possible after collection.
- Perform testing within 4 hours of sample collection or transfer plasma (avoiding platelet contamination) to polypropylene tube with plastic pipette for storage within two hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood or Plasma | Ambient or Refrigerated | 4 Hours |
| Plasma | Frozen (-18C) | 2 Weeks |
| Frozen (-70C) | 6 Months | |
| Frozen thawed | 2 Hours |
Rejection Criteria
| Specimens filled below the fill line |
|---|
| Specimens filled above the fill line |
| Clotted |
| Frozen whole blood |
| Known IV fluid or Hickman line fluid contamination |
| Specimens with abnormal results that have a Hct >55% that have not had the citrate anticoagulant adjusted |
| Reject at gross hemolysis |
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | 22.0 - 30.0 seconds |
| See Critical Value List for list of current critical values | |
Marshfield Labs Performing Department
Marshfield Labs Hematology
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Sunday | Less than 2 hours | Optical Clot Detection/Sysmex CS Series |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 85525 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 85525 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | APTT with Hep Neut |