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Test Code ARBOMSO Arbovirus IgM Antibody, Diagnostic Panel (SS02201)

Important Note

When ordering, provide onset date, travel history and symptoms.

Additional Codes

WSLH Test Code: SS02201

Useful For

Serodiagnosis of a recent infection with any of these agents in individuals with symptoms of arbovirus encephalitis with no other laboratory diagnosis.

 

Testing will not be performed as a screening test or on patients without symptoms of arbovirus infection.

Synonyms/Keywords

Eastern Equine Encephalitis, St. Louis Encephalitis, La Crosse Encephalitis, West Nile Virus, Jamestown Canyon Virus and Powassan Virus.

Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No CSF Sterile Container/Tube   3.0 mL 2.0 mL  
No Serum Red Top Tube (RTT) Serum Separator Tube (SST) 3.0 mL 1.0 mL  

Collection/Processing Instructions

PROVIDE ONSET DATE, TRAVEL HISTORY AND SYMPTOMS.  Specimens should be collected in the acute phase of illness.  Store and transport to WSLH at 2-8° Celsius (refrigerated with cool packs). 


If submitting CSF, a serum sample must also be sent for the same testing. Order two ARBOMSO tests, one for CSF and one for serum.  Testing will not be performed if only CSF is submitted. Must collect serum sample within 48 hours of CSF sample collection. Alternatively, serum may be submitted by itself. Indicate on sample and order if the sample is CSF or serum.  

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated 48 hours
Frozen >48 hours
Serum Refrigerated 48 hours
Frozen >48 hours

Rejection Criteria

Room Temperature

Test Components

Qualitative IgM testing for Eastern Equine Encephalitis, St. Louis Encephalitis, La Crosse Encephalitis, West Nile Virus, Jamestown Canyon Virus and Powassan Virus.

Test Information

Laboratory regulations require the following minimum information to be provided on the requisition form for a specimen to be accepted for testing: Patient name or unique identifier; date and time of collection, patient date of birth and sex, specimen type/site of collection, test request(s), clinician name and UPIN, and address for reporting results. Please be certain that name/identifier on the form matches that on the specimen label.

Interferences

Cross-reaction may occur between the arboviruses. Negative results on a single acute phase specimen do not rule out infection, as specimen may have been obtained prior to the development of an antibody response.

Interpretations

Negative, Presumptive Positive or Nonspecific for MIA assay.

Numeric value and interpretation as Negative, Equivocal, Presumptive Positive or Non-Specific for IgM capture ELISA. 

Performing Laboratory Name

Wisconsin State Lab of Hygiene

Referral Laboratory Information

Address Telephone Website Link Marshfield Lab Account #
465 Henry Mall
Madison, WI 53706
800-862-1013 www.slh.wisc.edu 700815

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Wisconsin State Lab of Hygiene (WSLH) Once weekly 2 to 8 days Qualitative IgM capture ELISA for JCV, POWV and LAC; Microsphere immunoassay (MIA) for WNV/SLE and EEE

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
86651   1 La Crosse Encephalitis  
86652   1 Eastern Equine Encephalitis  
86653   1 St. Louis Encephalitis  
86788   1 West Nile Virus IgM  
86790   2    

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
86651   1 La Crosse Encephalitis  
86652   1 Eastern Equine Encephalitis  
86653   1 St. Louis Encephalitis  
86788   1 West Nile Virus IgM  
86790   2