Test Code B2M Beta-2 Microglobulin
Useful For
Beta 2 microglobulin levels are useful as predicters of longevity in patients with multiple myeloma, and are useful in monitoring patients who have undergone renal transplants.
In inflammatory disorders (RA, SLE, Sjogren's Syndrome and Crohn's disease) and lymphoproliferative diseases (multiple myeloma, B cell lymphoma, CLL), serum B2M levels are frequently elevated reflecting an increased rate of synthesis. B2M levels in the serum are also useful for monitoring renal transplant patients.
Synonyms/Keywords
B2M, B2MICRO
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 0.5 mL | 0.4 mL | 0.3 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | 2 months |
Rejection Criteria
Plasma samples
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | 0.9-2.4 mg/L |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 6-8 hours | Turbidimetric method/The Binding Site Optilite analyzer |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82232 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82232 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Beta 2 Microglobulin |
| COM | Beta 2 Microglobulin - Blood |