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HelpTest Code BBTITER Antibody Titer
Useful For
Antibody Titer can assist in the diagnosis and management of HDFN (Hemolytic Disease of the Fetus and Newborn). When a prenatal patient has a positive antibody screen and the antibody specificity is either anti-D or other clinically significant IgG antibodies known to cause HDFN, titration studies are performed to determine the relative amount of the antibody. A clinically significant titer is generally considered to be 16 or higher, depending on the antibody specificity and institution.
Synonyms/Keywords
Indirect Coombs Antibody Titer, Prenatal Titer, Antibody Titration, Titration studies, BBTITER, ABSC
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Whole blood | Two 6 mL EDTA Pink Top Tubes (PTT) | Four 3 mL EDTA Lavender Top Tubes (LTT) OR Two 6 mL Red Top Tubes (RTT) | Two 6 mL | 6.0 mL | |
Collection/Processing Instructions
Indicate in Comment of test Antibody Titer" and specificity of antibody, if known (e.g. Antibody Titer; Anti-c").
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole blood/serum | Refrigerate | <10 days old |
Rejection Criteria
| Serum separator tubes (SST) |
|---|
| Frozen-if ABSC ordered |
| Hemolyzed |
Test Components
Titer, ABSC, Antibody Identification, Antigen Typing
Test Information
An antibody screenmay be performed to determine the presence of atypical antibodies. Ifpositive, antibody identification and antigen typing will be performed as partof confirmatory testing.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | No reference ranges are available. |
Marshfield Labs Performing Department
Marshfield Labs Transfusion Services
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Sunday | 2-4 hours | Serological |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86886 | Titer | |||
| 86850 | ABSC | |||
| 86905 | AGPAT | |||
| 86077 | PATH CONSULT |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86886 | Titer | |||
| 86850 | ABSC | |||
| 86905 | AGPAT | |||
| 86077 | CONSULT |