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Test Code BCA Breast Cancer Antigen 15-3

Useful For

Assay is useful for the monitoring of disease and response to therapy in patients with metastatic breast cancer, or monitoring recurrence in previously treated Stage II or Stage III breast cancer patients. The test is not sufficiently sensitive for early screening of breast cancer.

Synonyms/Keywords

Breast Ca Ag 15-3 (BCA)

Specimen Requirements

 

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No Plasma/Serum Lithium Heparin Plasma Separator Tube (PST) Lithium Heparin Green Top Tube (GTT), Serum Separator Tube (SST), Red Top Tube (RTT) 1 mL 0.5 mL 0.3 mL

Specimen Stability Information

 

Specimen Type Temperature Time

Plasma/Serum
 
Ambient 8 hours
Refrigerated 2 days
Frozen >2 days

Thaw samples only once

 

Rejection Criteria

Gross hemolysis or Icterus

Test Information

Assay measures CA15-3 antigen. Test is useful for the monitoring of disease and response to therapy in patients with metastatic breast cancer, or monitoring recurrence in previously treated Stage II or Stage III breast cancer patients. The test is not sufficiently sensitive for early screening of breast cancer.

 

An alternative marker for breast cancer antigen also exists known as CA27.29. Clinically, both CA15-3 and CA27.29 give similar clinical information although differences in results will be seen with individual patients. Accordingly, the two assays should not be used interchangeably for serial monitoring in a given patient.

Reference Range Information

Performing Location Reference Range
Marshfield ≤ 35 U/mL 

Marshfield Labs Performing Department

Marshfield Labs Chemistry

Performing Information

 

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield Monday through Friday Less than 2 hours Beckman Coulter DXI

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
86300        

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
86300        

Ordering Applications

Ordering Application Description
Cerner Breast Cancer Antigen 15-3