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HelpTest Code BHYPSSO Hypersensitivity Pneumonitis Panel, Immunoglobulin G, Serum
Additional Codes
Mayo Test Code: BHYPS
Ordering Guidance
This is a panel of tests which includes serology for: Alternaria tenuis/alternata, Aspergillus fumigatus, Aureobasidium pullulans, Laceyella sacchari, Micropolyspora faeni, Penicillium chrysogenum/notatum, Phoma betae, and Trichoderma viride. If only Aspergillus fumigatus is requested, order SASP / Aspergillus fumigatus, IgG Antibodies, Serum.
Specimen Required
Container/Tube: Sarstedt Aliquot Tube, 5 mL (T914)
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 0.5 mL Serum
Collection Information: Centrifuge and aliquot serum into a plastic vial.
Useful For
Evaluation of patients suspected of having hypersensitivity pneumonitis induced by exposure to Alternaria tenuis/alternata, Aspergillus fumigatus, Aureobasidium pullulans, Laceyella sacchari, Micropolyspora faeni, Penicillium chrysogenum/notatum, Phoma betae, and Trichoderma viride
Method Name
Fluorescence Enzyme Immunoassay (FEIA)
Reporting Name
Hypersensitivity Pheum Panel,IgG, SSpecimen Type
SerumSpecimen Minimum Volume
Serum: 0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 28 days |
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Alternaria alternata, IgG antibody: ≤19.0 mg/L
Aspergillus fumigatus, IgG antibody: ≤102.0 mg/L
Aureobasidium pullulans, IgG antibody: ≤16.0 mg/L
Laceyella sacchari, IgG antibody: ≤45.0 mg/L
Micropolyspora faeni, IgG antibody: ≤6.0 mg/L
Penicillium chrysogenum, IgG antibody: ≤94.0 mg/L
Phoma betae, IgG antibody: ≤16.0 mg/L
Trichoderma viride, IgG antibody: ≤16.0 mg/L
Cautions
IgG antibodies to Alternaria tenuis/alternata, Aspergillus fumigatus, Aureobasidium pullulans, Laceyella sacchari, Micropolyspora faeni, Penicillium chrysogenum/notatum, Phoma betae, and Trichoderma viride may be found in sera from healthy individuals; the presence of these specific antibodies is not sufficient to establish the diagnosis of hypersensitivity pneumonitis.
Elevated concentration of antibodies to Aspergillus fumigatus may be also found in patients with invasive aspergillosis and cavitary lung disease.
The concentrations of antibodies to these antigens may decrease following treatment, although elevated concentrations may persist in treated patients.
The test method utilizes the fluorescence enzyme immunoassay (FEIA) on Phadia ImmunoCAP 250. Values obtained using the same test system or different assay methods cannot be used interchangeably. Alternative reference values established utilizing the same reagents or test system may be influenced by the characteristics of the local cohorts and environmental exposures.
Day(s) Performed
Monday through Friday
Report Available
2 to 5 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86001 x 8
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| BHYPS | Hypersensitivity Pheum Panel,IgG, S | 35577-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| BH01 | Alternaria alternata, IgG Ab | 26951-4 |
| BH02 | Aspergillus fumigatus, IgG Ab | 26954-8 |
| BH03 | Aureobasidium pullulans, IgG Ab | 26955-5 |
| BH04 | Laceyella sacchari, IgG Ab | 105270-3 |
| BH05 | Micropolyspora faeni, IgG Ab | 26948-0 |
| BH06 | Penicillium chrysogenum, IgG Ab | 26957-1 |
| BH07 | Phoma betae, IgG Ab | 35551-1 |
| BH08 | Trichoderma viride, IgG Ab | 49687-7 |
| BH09 | Hypersensitivity Interpretation | 69048-7 |