Home
HelpTest Code CCP Cyclic Citrullinated Peptide Antibodies
Useful For
Detection of CCP antibodies is used as an aid in the diagnosis of rheumatoid arthritis. Measurements of anti-CCP may provide important information regarding the severity and prognosis of the disease.
See the Mixed Connective Tissue Disease Panel Algorithm for suggested testing strategy.
Synonyms/Keywords
CCP, Rheumatoid Arthritis, Avise MCV
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) or Serum Separator Tube (SST) | 1.0 mL | 0.4 mL | 0.4 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
| Gross hemolysis |
|---|
| Gross lipemia |
| Gross Icterus |
Test Information
A positive result for CCP antibodies indicates a high likelihood of RA. However, not all RA patients are positive for CCP antibodies. Results of this assay should be used in conjunction with clinical findings and other serological tests.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | Negative: <3.0 U/mL |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86200 | 1 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86200 | 1 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Centricity | Cyclic Citrullinated Peptide |
| Cerner | Cyclic Citrulline Peptide |