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HelpTest Code CHLAPSO Chlamydia IgM and IgG Panel, Immunofluorescence, Serum
Additional Codes
Mayo Test Code: CHLAP
Ordering Guidance
For suspected Chlamydia trachomatis infection, order either CTRNA / Chlamydia trachomatis, Nucleic Acid Amplification, Varies or CGRNA / Chlamydia trachomatis and Neisseria gonorrhoeae, Nucleic Acid Amplification, Varies.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.6 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Aiding in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infection
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| CHLG | Chlamydia IgG, IFA, S | Yes | Yes |
| CHLM | Chlamydia IgM, IFA, S | Yes | Yes |
Method Name
Micro-Immunofluorescent Antibody (MIF) Assay
Reporting Name
Chlamydia IgM/IgG Panel, IFA, SSpecimen Type
SerumSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 30 days |
| Frozen | 30 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Heat-inactivated specimen | Reject |
Reference Values
Chlamydia pneumoniae
IgM: <1:10
IgG: <1:64
Chlamydia psittaci
IgM: <1:10
IgG: <1:64
Cautions
Antichlamydial IgG can persist for years. All results from chlamydial serologies must correlate with clinical history and other data available to the physician.
Specimens collected too early during primary infection may not contain detectable antibodies. If chlamydial infection is suspected, a second specimen should be collected 10 to 21 days later and tested in parallel with the original specimen.
During a primary Chlamydia infection, the early antibody response may be cross-reactive with multiple Chlamydia species.
This assay does not report antibodies detected against Chlamydia trachomatis. Sera from suspected cases of lymphogranuloma venereum (LGV) should be tested by a Lymphogranuloma Venereum Differentiation Antibody Panel. LGV testing is not performed by Mayo Clinic Laboratories; call 800-533-1710 for assistance.
Due to the limited sensitivity and specificity of Chlamydia serologic tests, patients with suspected C trachomatis infection should be tested by a molecular method (eg, CTRNA / Chlamydia trachomatis, Nucleic Acid Amplification, Varies or CGRNA / Chlamydia trachomatis and Neisseria gonorrhoeae, Nucleic Acid Amplification, Varies) to evaluate for current/active infection.
Day(s) Performed
Monday
Report Available
Same day/1 to 4 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
86632 x 2
86631 x 2
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CHLAP | Chlamydia IgM/IgG Panel, IFA, S | 77166-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 619392 | C. pneumoniae IgG | In Process |
| 619390 | C. pneumoniae IgM | In Process |
| 619391 | C. psittaci IgM | In Process |
| 619393 | C. psittaci IgG | In Process |
Forms
If not ordering electronically, complete, print, and send an Infectious Disease Serology Test Request (T916) with the specimen.