Test Code CMV Cytomegalovirus Antibody, IgG and IgM
Synonyms/Keywords
CMV Antibody, Anti-CMV IgG/IgM
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Serum Separator Tube (SST) | Red Top Tube (RTT) | 1.0 mL | 0.5 mL | 0.5 mL |
Collection/Processing Instructions
Specimens collected in gel-barrier tubes should be centrifuged within one hour of collection.
Specimens collected in gel-barrier tubes must be removed from the primary tube prior to transporting to Marshfield. Do not send primary collection tube.
Serum from samples collected in an RTT must be removed from the clot within one hour for storage or transport.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated | 7 days |
| Frozen | > 7 days |
Rejection Criteria
Hemolyzed specimens, Lipemic specimens
Interpretations
A positive IgG generally indicates infection with CMV at some time. The simultaneous detection of IgM antibodies signifies recent infection or reactivation of latent infection.
General interpretive guidelines:
- IgG Negative: Not infected or very early infection
- IgG Positive: Infected
- IgG Positive / IgM Negative: Prior exposure at indeterminate time.
- IgG Positive / IgM Positive: Suggests acute infection.
- IgG Negative / IgM Positive: Early disease, re-activation, or false-positive IgM. Repeat in 2-3 weeks.
- Equivocal Results: Indeterminate. Retest if clinically indicated.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield |
IgM: Negative IgG: Negative |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday and Friday | 1 day | Multiplex Immunoassay/Biorad Bioplex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86644 | 1 | CMV IgG | ||
| 86645 | 1 | CMV IgM |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86644 | 1 | CMV IgG | ||
| 86645 | 1 | CMV IgM |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Cytomegalovirus Antibody IgG and IgM |