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Test Code CMV Cytomegalovirus Antibody, IgG and IgM

Synonyms/Keywords

CMV Antibody,  Anti-CMV IgG/IgM

Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No Serum Serum Separator Tube (SST) Red Top Tube (RTT) 1.0 mL 0.5 mL 0.5 mL

Collection/Processing Instructions

Specimens collected in gel-barrier tubes should be centrifuged within one hour of collection.

 

Specimens collected in gel-barrier tubes must be removed from the primary tube prior to transporting to Marshfield. Do not send primary collection tube.

 

Serum from samples collected in an RTT must be removed from the clot within one hour for storage or transport.

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated 7 days
Frozen > 7 days

Rejection Criteria

Hemolyzed specimens, Lipemic specimens

Interpretations

A positive IgG generally indicates infection with CMV at some time. The simultaneous detection of IgM antibodies signifies recent infection or reactivation of latent infection.  

 

General interpretive guidelines:

  • IgG Negative: Not infected or very early infection
  • IgG Positive: Infected
  • IgG Positive / IgM Negative: Prior exposure at indeterminate time.
  • IgG Positive / IgM Positive: Suggests acute infection.
  • IgG Negative / IgM Positive: Early disease, re-activation, or false-positive IgM. Repeat in 2-3 weeks.
  • Equivocal Results: Indeterminate. Retest if clinically indicated.

Reference Range Information

Performing Location Reference Range
Marshfield

IgM: Negative

IgG: Negative

Marshfield Labs Performing Department

Marshfield Labs Immunodiagnostics

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield Monday and Friday 1 day Multiplex Immunoassay/Biorad Bioplex 2200 

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
86644   1 CMV IgG  
86645   1 CMV IgM  

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
86644   1 CMV IgG  
86645   1 CMV IgM  

Ordering Applications

Ordering Application Description
Cerner Cytomegalovirus Antibody IgG and IgM