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HelpTest Code CO-BUP Buprenorphine, Urine, Confirm Only by LCMS
Useful For
Detecting exposure to buprenorphine to monitor compliance in taking prescribed medications or to detect abuse
Synonyms/Keywords
Buprenex, Suboxone, Subutex, Temgesic
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Urine | Sage urine collection container | Sterile plastic container with no preservatives | 7 mL | 5 mL | 3 mL |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Refrigerate (Preferred) | 14 days |
| Ambient | 14 days |
Test Information
This test was developed and its performance characteristics determined by Marshfield Labs. It has not been cleared or approved by the US Food and Drug Administration. This test is used for clinical purposes. It should not be regarded as investigational or for research.
This test is a LCMS confirmation only for Buprenorphone. It is intended for use only in patients where an initial drug screening test has already been performed at the time of the specimen collection (i.e. Point-of-Care drug screening cup, dipstick, etc...). The specimen will not be screened by immunoassay in the laboratory; it will only be tested by LCMS.
This test will detect the presence of buprenorphine and its metabolite norbuprenorphine.
Buprenorphine is a member of the opioid family and is used as an alternative to methadone in the treatment of heroin addiction and as an analgesic for treatment of moderate to severe pain. Buprenorphine is metabolized to norbuprenorphine. Measurement of buprenorphine and norbuprenorphine assist the clinician in determining patient compliance with treatment.
Interpretations
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | Negative. Positives are reported with a quantitative LC-MS/MS result. |
Marshfield Labs Performing Department
Marshfield Labs Special Chemistry
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 2-4 days | Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS) using Multiple Reaction Monitoring |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 80348 | 1 | Buprenorphine Confirmation by LCMS | ||
| G0480 | 1 | Buprenorphine Confirmation by LCMS | For Marshfield Clinic and Medicare/Medicaid |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 80348 | 1 | Buprenorphine Confirmation by LCMS | ||
| G0480 | 1 | Buprenorphine Confirmation by LCMS | For Medicare/Medicaid |
Ordering Applications
| Ordering Application | Description |
|---|---|
| COM | Buprenorphine Confirm, Urine |
| Cerner | Buprenorphine, Urine, Confirm Only |