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HelpTest Code CO-COC Cocaine Metabolite, Urine, Confirm Only by LCMS
Useful For
Detecting abuse of cocaine
Synonyms/Keywords
Benzoylecgonine
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Urine | Sage urine collection container | Sterile plastic container with no preservatives | 5 mL | 3 mL | 1.5 mL |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Ambient | 72 hours |
| Refrigerate (Preferred) | 30 days |
Test Information
This test was developed and its performance characteristics determined by Marshfield Labs. It has not been cleared or approved by the US Food and Drug Administration. This test is used for clinical purposes. It should not be regarded as investigational or for research.
Cocaine is prepared from the leaves of the tropical bush Erythroxylon coca. After use (snorting, smoking, or intravenous injection) cocaine is metabolized to benzoylecgonine (BZE) and ecgonine methyl ester (EME). The BZE metabolite is analyzed since it is the metabolite that is detectable in urine for a longer period of time.
This LC-MS/MS confirmation-only test for BZE is intended for use only in patients where an initial drug screening test has already been performed at the time of specimen collection (i.e. point-of-care drug screening cup, dipstick, etc.). The specimen will not be screened by immunoassay in the laboratory; it will only be tested by LC-MS/MS.
Interpretations
Current Cutoff Levels for Toxicology
The cocaine metabolite benzoylecgonine can be detected up to 3-5 days after last use.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | ALL: Negative. Positives are reported with a quantitative LC-MS/MS result. |
Marshfield Labs Performing Department
Marshfield Labs Special Chemistry
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 2-4 days | Liquid Chromatography/Tandem Mass Spectrometry (LCMS/MS) using Multiple Reaction Monitoring |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 80353 | 1 | Cocaine Metabolite Confirm by LC/MS/MS | ||
| G0480 | 1 | Cocaine Metabolite Confirm by LC/MS/MS | For Marshfield Clinic and Medicare/Medicaid |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 80353 | 1 | Cocaine Metabolite Confirm by LC/MS/MS | ||
| G0480 | 1 | Cocaine Metabolite Confirm by LC/MS/MS | For Medicare/Medicaid |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Cocaine Metabolite, Urine, Confirm Only by LCMS |
| COM | Cocaine, Urine, Confirm |