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HelpTest Code CTDP Connective Tissue Disease Panel
Useful For
For the screening and diagnosis of patients with symptoms of mixed connective tissue diseases such as systemic lupus erythematosus, systemic sclerosis, myositis, Sjogren's syndrome, and rheumatoid arthritis.
See the Mixed Connective Tissue Disease Panel Algorithm for suggested follow-up testing.
Synonyms/Keywords
Rheumatoid Arthritis, RA, RA-IgM, Lupus, SLE, CREST syndrome, Sjogren's syndrome, scleroderma, polymyositis, dermatomyositis
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 1.5 mL | 1.0 mL | 1.0 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 2 days |
| Frozen | > 2 days |
Rejection Criteria
| Gross hemolysis |
|---|
| Gross lipemia |
| Heat inactivated samples |
| Gross icterus |
Test Components
This panel tests for Rheumatoid Factor (RA-IgM), Cyclic Citrullinated Peptide (CCP), and Antinuclear antibodies (ANA).
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield |
RA: ≤13 IU/mL ANA: Negative CCP: 0 - 2.9 IU/mL |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 2 days |
RA: Turbidimetric Method (Binding Site/Optilite) ANA: Indirect Immunofluorescence CCP:Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86200 | 1 | CCP | ||
| 86431 | 1 | RA | ||
| 86038 | 1 | ANA |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86200 | 1 | CCP | ||
| 86431 | 1 | RA | ||
| 86038 | 1 | ANA |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Connective Tissue Disease Pnl |
| COM | Connective Tissue Disease Pnl |