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HelpTest Code F8INHP Factor VIII Inhibitor Panel
Synonyms/Keywords
Inhibitor
Specimen Requirements
| Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|
| *Platelet Poor Plasma | 3.2% Citrated Blue Top Tube (BTT) | Two 0.75 mL aliquots | Two 0.75 mL aliquots | 0.75 mL |
Collection/Processing Instructions
Note: This is the recommended test for the initial demonstration of the presence of an inhibitor of factor VIII. A factor VIII will be performed and if the level is within the reference range, an inhibitor is not present and no further testing is indicated. In the event that the factor VIII level is below the lower limit of the reference range, an inhibitor assay will be performed to determine the strength of the inhibitor.
Two 0.75 mL citrated Blue Top Tube (BTT) plasma aliquots. (If more than one coagulation test is ordered, a separate aliquot is needed for each test.)
- Collect in Citrated Blue Top Tube (BTT)
- Citrate anticoagulant must be adjusted for HCT >55%
- Tubes must be at least 90% full
- Invert completely 3-4 times (without shaking) to mix
*See Instructions for: Preparation of Platelet Poor Plasma
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma | Frozen | 6 months |
Rejection Criteria
| Clotted or Hemolyzed |
|---|
| Contamination with IV or Hickman Line fluids |
| Specimens that thaw during storage or transport |
Test Information
Note: This is the recommended test for the initial demonstration of the presence of an inhibitor of factor VIII. A factor VIII will be performed and if the level is within the reference range, an inhibitor is not present and no further testing is indicated. In the event that the factor VIII level is below the lower limit of the reference range, an inhibitor assay will be performed to determine the strength of the inhibitor.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield |
Factor 8 (VIII): 60-135% Factor VIII Inhibitor: 0.0 Bethesda Units |
Marshfield Labs Performing Department
Marshfield Labs Hematology
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday and Thursday | 2 - 4 hours | Siemens CS2500 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 85240 | Factor 8 (VIII) Activity Assay | |||
| 85335 | Factor Inhibitor | Charge as needed |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 85240 | Factor 8 (VIII) Activity Assay | |||
| 85335 | Factor Inhibitor | Charge as needed |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Centricity | Factor VIII-Inhibitor Panel |
| Cerner | Factor VIII Inhibitor Panel |
| COM | Factor VIII Inhibitor Panel |