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Test Code FELB Felbamate

Useful For

This test is useful for monitoring felbamate in blood.  Felbamate is a relatively non-toxic drug that is not associated with major side effects in higher concentrations

Synonyms/Keywords

Felbatol

Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No Serum Red Top Tube (RTT)   0.5 mL 0.5 mL 0.3 mL

Collection/Processing Instructions

Specimen should be collected prior to dosing.  Please indicated collection time.

Separate serum/plasma from cells within 2 hours of collection.

Specimen Stability Information

Specimen Type Temperature Time
Serum Ambient 48 hrs
Refrigerate 2 weeks
Frozen 2 weeks

Rejection Criteria

Specimens collected in serum or plasma separator tubes

Test Information

This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.

Interpretations

Trough concentrations are most accurate and recommended for therapeutic drug monitoring. Preferably obtained just before the next dose.

Reference Range Information

Performing Location Reference Range
Marshfield Patients receiving a maximum 3600 mg dose show typical serum felbamate levels of 50-80 ug/mL with a range of 25-135 ug/mL, without toxicity.

Marshfield Labs Performing Department

Marshfield Labs Special Chemistry

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield Monday, Wednesday, Friday 1 day UPLC MS/MS - Waters Acquity UPLC, XEVO TQ-S Tandem Mass Spectrometry System
Samples must be in performing department by 8am on day of testing for results the same day. Testing may be batched and set up on alternative days of the week as needed. 

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
80167   1    

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
80167   1    

Ordering Applications

Ordering Application Description
Cerner Felbamate Level