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HelpTest Code GBM Glomerular Basement Membrane Antibodies
Useful For
Detects IgG autoantibodies against the glomerular basement membrane (GBM), specifically the C-terminal end of type IV collagen. In conjuction with clinical findings of lung hemorrhage and rapidly progressive renal failure, autoantibodies to GBM support the diagnosis of Goodpasture’s syndrome. GBM autoantibodes also may occur in other glomerular diseases.
Synonyms/Keywords
Anti-GBM, Basement membrane, GBM
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) or Serum Separator Tube (SST) | 0.5 mL | 0.5 mL | 0.2 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
| Gross lipemia |
|---|
| Gross hemolysis |
| Heat inactivated samples |
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | Negative <1.0 |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 83516 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 83516 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Centricity | Glomerular Basement Membrance AB |
| Cerner | Glomerular Basement Membrane Antibodies |