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HelpTest Code HAPTO Haptoglobin
Useful For
This test is useful for monitoring haptoglobin levels in serum.
The haptoglobin system is an important mechanism for iron conservation. Decreased values are seen with any hemolytic disorder or process that damages red blood cells. Increased inflammatory conditions, some malignancies, tissue damage, corticosteroid and estrogen therapy.
Synonyms/Keywords
Haptoglobin
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 0.5 mL | 0.4 mL | 0.3 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | 3 months |
Rejection Criteria
| Hemolysis |
|---|
| Plasma samples |
Interpretations
Haptoglobin is an alpha-2 globulin that acts as a scavenger of free hemoglobin by formation of a complex. The hemoglobin/haptoglobin complex is large enough to prevent loss by filtration in the kidneys. The complex is then catabolized the the Reticulo Endothial System and the iron is recycled. This is an important mechanism for iron conservation. Decreased values are seen with any hemolytic disorder or process that damages red blood cells. Haptoglobin is also an acute phase reactant, and its synthesis is stimulated by inflammatory conditions (leading to increase levels). Increased levels are also seen in certain malignancies, tissue damage with burns, and with corticosteroid and estrogen therapy.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | 50-220 mg/dL |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 6-8 hours | Turbidimetric method/The Binding Site Optilite analyzer |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 83010 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 83010 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Haptoglobin |
| COM | Haptoglobin |