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HelpTest Code HSVZVP Herpes Simplex and Varicella Zoster NAT Panel
Useful For
Useful for detection and differentiation of VZV, HSV I and II DNA in CSF and vesicular and cellular material from base of lesion (cutaneous or mucocutaneous only).
Please note this test should not be used for screening asymptomatic patients. In suspected cases of congenital herpes, order MISC for VHSV culture to Mayo Laboratories.
This test can also not be used for sources other than those listed above, including ocular specimens. For this testing, order MISC for HSVPV and VZVPV to Mayo Laboratories.
Synonyms/Keywords
HSV and VZV by PCR, Derm panel
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | CSF | Sterile, leak-proof vial |
|
1.0 mL | 0.5 mL | 0.2 mL |
| No | Swab - skin lesions | Universal Transport Media (UTM) | BD UVT, Remel M4, Remel M4RT, Remel M5, Remel M6 | 1 swab |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| CSF |
Refrigerate | 7 days |
| Frozen | 30 days | |
| Swab | Refrigerate | 7 days |
Rejection Criteria
| Wood-Shafted, Cotton, or Calcium Alginate Swabs |
| Urine and Body Fluids (With the Exception of CSF) |
| Solid Tissue Samples |
Test Components
HS12PCR, VZVPCR
Test Information
HSVZVPCR is a real-time polymerase chain reaction (PCR) based qualitative in vitro diagnostic test for the direct amplification and detection of HSV-1, HSV-2 and VZV DNA from unprocessed cutaneous and mucocutaneous lesion swab specimens and CSF.
Negative results do not preclude VZV, HSV-1 or HSV-2 infection and should not be used as the sole basis for treatment or other patient management decisions.
Reference Range Information
Interpretive report
Marshfield Labs Performing Department
Marshfield Labs Molecular Pathology
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Molecular Pathology | Lesions: Monday through Friday CSF: Monday through Sunday |
6-8 hours* | Real time PCR |
| *Testing performed once/day. Sample must be received in the lab by 0400 to be tested same day. | |||
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 87529 | 2 | HSV | ||
| 87798 | 1 | VZV |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 87529 | 2 | HSV | ||
| 87798 | 1 | VZV |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Centricity | None |
| Cerner | Herpes Simplex and Varicella Zoster NAT Panel |