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HelpTest Code LEVE Levetiracetam, Serum
Useful For
This test is useful for monitoring leviteracetam (anticonvulsant) levels. Leviteracetam is approved for adjunctive therapy in the treatment of partial onset seizures in adults and children, 4 years or older, with epilepsy
Synonyms/Keywords
Keppra, Leviteracetam
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | 0.5 mL | 0.5 mL | 0.3 mL |
Collection/Processing Instructions
Separate serum/plasma from cells within 2 hours of collection.
Specimens collected in serum separator tube (SST) will be rejected.
Heparinized or ETDA plasma collected in a green top or lavender top tube will be rejected
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Ambient | 48 hours |
| Refrigerate | 2 weeks | |
| Frozen | 3 months |
Rejection Criteria
Specimens collected in a serum or plasma separator tube
Test Information
This test was developed and its performance characteristics determined by Marshfield Labs. It has not been cleared or approved by the US Food and Drug Administration. This test is used for clinical purposes. It should not be regarded as investigational or for research.
Interpretations
Trough concentrations are most accurate and recommended for therapeutic drug monitoring. Preferably obtained just before the next dose.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield |
Peak concentration: 10-63 ug/mL Trough concentration: 3-34 ug/mL |
Marshfield Labs Performing Department
Marshfield Labs Special Chemistry
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday, Wednesday, Friday | 6-8 hours | UPLC MS/MS - Waters Acquity UPLC, XEVO TQ-S Tandem Mass Spectrometry System |
| Samples must be in performing department by 8am on day of testing for results the same day. Testing may be batched and set up on alternative days of the week as needed. | |||
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 80177 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 80177 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| COM | Levetiracetam |
| Cerner | Levetiracetam Level |