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Test Code MIX Mixing Study

Synonyms/Keywords

Mixing Study, Factor Identification

Specimen Requirements

 

Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume
*Platelet Poor Plasma 3.2% Citrated Blue Top Tube (BTT)   3-4 1.5 mL aliquots of citrated plasma (SeeCollection Processing Instructions)

 

Collection/Processing Instructions

Citrated Plasma (BBT): Collect in approximately 3-4 Citrated Blue Top Tubes (BTT), aliquot each.

  • Citrate anticoagulant must be adjusted for HCT >55%.
  • Tube must be at least 90% full.
  • Invert completely 3-4 times (without shaking) to mix.


*See Instructions for: Preparation of Platelet Poor Plasma

Specimen Stability Information

Specimen Type Temperature Time
Platelet Poor Plasma Ambient 4 hours
Frozen 6 months

Rejection Criteria

Clotted or Hemolyzed
Contamination with IV or Hickman line fluid
Specimens that thaw during storage or tansport
Specimen tubes under/ over filled from the fill line

Test Components

Prothrombin Time, Activated Partial Thromboplastin Time, PT and APTT Mixing Studies

Interpretations

Reflex testing for PT and APTT substitutions, factor assays and/or circulating inhibitor assays (DRVVT and SCT) will be performed based on the results of the PT (INR), APTT, mixing studies and the basic coagulation scheme.

Reference Range Information

Performing Location Reference Range
Marshfield See individual test listings for reference ranges.

Marshfield Labs Performing Department

Marshfield Labs Coagulation

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield APTT/PT: Monday- Friday 6-8 hours Siemens Sysmex CS2500
Other reflex testing 6-8 hours  

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
85730     APTT  
85610     Protime/INR  
85732     APTT Mix Study If needed
85611     PT Mix Study If needed
85613     DRVVT If needed
85732     SCT  If needed
Varies     Factor assays vary with follow-up If needed

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
85730     APTT  
85610     Protime/INR  
85732     APTT Mix Study If needed
85611     PT Mix Study If needed
85613     DRVVT If needed
85732     SCT If needed
Varies     Factor assays vary with follow-up If needed

Ordering Applications

Ordering Application Description
Cerner Powerchart MIX
4medica Mixing Study