Test Code MIX Mixing Study
Synonyms/Keywords
Mixing Study, Factor Identification
Specimen Requirements
| Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume |
|---|---|---|---|
| *Platelet Poor Plasma | 3.2% Citrated Blue Top Tube (BTT) | 3-4 1.5 mL aliquots of citrated plasma (SeeCollection Processing Instructions) |
Collection/Processing Instructions
Citrated Plasma (BBT): Collect in approximately 3-4 Citrated Blue Top Tubes (BTT), aliquot each.
- Citrate anticoagulant must be adjusted for HCT >55%.
- Tube must be at least 90% full.
- Invert completely 3-4 times (without shaking) to mix.
*See Instructions for: Preparation of Platelet Poor Plasma
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Platelet Poor Plasma | Ambient | 4 hours |
| Frozen | 6 months |
Rejection Criteria
| Clotted or Hemolyzed |
|---|
| Contamination with IV or Hickman line fluid |
| Specimens that thaw during storage or tansport |
| Specimen tubes under/ over filled from the fill line |
Test Components
Prothrombin Time, Activated Partial Thromboplastin Time, PT and APTT Mixing Studies
Interpretations
Reflex testing for PT and APTT substitutions, factor assays and/or circulating inhibitor assays (DRVVT and SCT) will be performed based on the results of the PT (INR), APTT, mixing studies and the basic coagulation scheme.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | See individual test listings for reference ranges. |
Marshfield Labs Performing Department
Marshfield Labs Coagulation
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | APTT/PT: Monday- Friday | 6-8 hours | Siemens Sysmex CS2500 |
| Other reflex testing | 6-8 hours |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 85730 | APTT | |||
| 85610 | Protime/INR | |||
| 85732 | APTT Mix Study | If needed | ||
| 85611 | PT Mix Study | If needed | ||
| 85613 | DRVVT | If needed | ||
| 85732 | SCT | If needed | ||
| Varies | Factor assays vary with follow-up | If needed |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 85730 | APTT | |||
| 85610 | Protime/INR | |||
| 85732 | APTT Mix Study | If needed | ||
| 85611 | PT Mix Study | If needed | ||
| 85613 | DRVVT | If needed | ||
| 85732 | SCT | If needed | ||
| Varies | Factor assays vary with follow-up | If needed |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner Powerchart | MIX |
| 4medica | Mixing Study |