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HelpTest Code MPHEND Methylphenidate and Metabolite, Urine
Useful For
Detecting the presence of methylphenidate and its major metabolite, ritalinic acid, in urine to confirm abuse or to monitor compliance.
Synonyms/Keywords
Ritalin, Concerta, Metadate
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Urine | Sage urine collection container | Sterile plastic container with no preservatives | 5 mL | 3 mL | 1.5 mL |
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Ambient | 48 hours |
| Refrigerate | 14 days |
Test Information
This test was developed and its performance characteristics determined by Marshfield Labs. It has not been cleared or approved by the US Food and Drug Administration. This test is used for clinical purposes. It should not be regarded as investigational or for research.
This test is a urine LCMS/MS confirmation for methylphenidate (Ritalin) and its major metabolite, ritalinic acid. Methylphenidate is prescribed for various disorders such as Attention Deficit Hyperactivity Disorder (ADHD), fatigue, and narcolepsy. It is a central nervous system stimulant similar in chemical structure and effect to amphetamine. It can be abused, particularly for relief of fatigue. It can have a strong stimulating effect on people who use it for non-medical reasons and is very addictive.
Interpretations
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | Negative. Positives are reported with a quantitative LCMS/MS result. |
Marshfield Labs Performing Department
Marshfield Labs Special Chemistry
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 2-4 days | Liquid Chromatography/Tandem Mass Spectrometry (LCMS/MS) using Multiple Reaction Monitoring |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 80360 | 1 | Methylphenidate and Metabolite | ||
| G0480 | 1 | Methylphenidate and Metabolite | For Marshfield Clinic and Medicare/Medicaid |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 80360 | 1 | Methylphenidate and Metabolite | ||
| G0480 | 1 | Methylphenidate and Metabolite | For Medicare/Medicaid |
Ordering Applications
| Ordering Application | Description |
|---|---|
| COM |
Methylphenidate, Urine |
| Cerner | Methylphenidate and Metabolite, Urine |