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HelpTest Code NBILI Bilirubin, Neonatal
Useful For
Elevated serum bilirubin concentrations are associated with the development of yellow staining of the brain, kernicterus, and brain injury resulting in spasticity, hearing loss, and mental retardation.
Synonyms/Keywords
NBili, Neonatal Bilirubin
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Plasma/Serum | Lithium-heparin Plasma Separator (PST), Serum Separator Tube (SST) | Lithium or Sodium-heparin Green Top (GTT), Red Top Tube (RTT), Red or Green Microcollection tube |
0.1 mL | 0.1 mL | 0.1 mL serum or plasma from 0.3mL whole blood |
Collection/Processing Instructions
Protect from light.
Samples collected in a RTT or GTT must be removed from cells within one hour for storage or transport.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma/Serum | Refrigerate | 2 days |
| Frozen | >2 days |
Rejection Criteria
| Samples not protected by light |
|---|
| Significantly hemolyzed samples cannot be assayed for Direct Bilirubin |
| Drug Eltrombopag: interferes with the total bilirubin assays. |
Test Components
Total Bilirubin, Direct Bilirubin
Indirect Bilirubin will be calculated
Interferences
Hemolysis will falsely decrease Direct Bilirubin.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| All Performing Sites | Total: 0-14 days: ≤11.0 mg/dL Total: 15 days-<1yr: ≤0.7 mg/dL Total: 1-<9yr: ≤0.4 mg/dL Direct: ≤14 days: ≤0.5 mg/dL Direct: ≥15 days: ≤0.3 mg/dL |
| See Critical Value List for list of current critical values. | |
Marshfield Labs Performing Department
Marshfield Labs Chemistry
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Beaver Dam | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Weston | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Eau Claire | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Park Falls | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Ladysmith | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Rice Lake | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Marshfield | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Minocqua | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Neillsville | Monday through Sunday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
| Stevens Point | Monday through Saturday | Less than 2 hours | Diazonium Salt/DPD Endpoint Assay/ Beckman AU |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82247 | 1 | Bilirubin, total | ||
| 82248 | 1 | Bilirubin, direct |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82247 | 1 | Bilirubin, total | ||
| 82248 | 1 | Bilirubin, direct |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Bilirubin Total Pediatric |