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Test Code PANELA Pancreatic Elastase, Fecal

Useful For

Diagnosis or the exclusion of exocrine pancreatic insufficiency, which may be associated with chronic pancreatitis, cystic fibrosis, carcinoma of the pancreas, diabetes mellitus type 1 (insulin-dependent diabetes mellitus), Shwachman-Diamond syndrome, and other etiologies of pancreatic insufficiency. 

Synonyms/Keywords

PE1, Elastase, Pancreatic, Pancreatic Elastase

Specimen Requirements

 

Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Stool (unpreserved, random) Sage container (screw-capped plastic vial) Sterile container 3 grams 1 gram (This volume does not allow for repeat testing)

 

Collection/Processing Instructions

Do not contaminate outside of container. Do not overfill container. Do not use a preservative. Specimens should be transported refrigerated (ice packs) or frozen if transport temperature is expected to exceed 40oC (104oF).

Specimen Stability Information

Specimen Type Temperature Time

Stool



 
Ambient 8 hours
Refrigerate 7 days
Frozen 12 months
Freeze/thaw cycle Stable x 2
Note: Pancreatic elastase can be performed on the same extracted stool sample as Fecal Calprotectin (CALP). Extracted stool samples will be kept 7 days from Final report. If PANELA is requested as an add-on, please call the lab for more information. 

Rejection Criteria

Serum or plasma received

Stool contaminated with urine

Preserved stool received

Specimens outside of the stability requirements

Very hard stool

Stool with excess mucous

Reference Range Information

Performing Location Reference Range
Marshfield
Normal: >200 ug elastase/g fecal material
Moderate pancreatic insufficiency: 100-200 ug elastase/g fecal material
Severe pancreatic insufficiency: <100 ug elastase/g fecal material

Marshfield Labs Performing Department

Marshfield Labs Microbiology

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield Tuesday, Thursday 1 day Chemiluminescence Immunoassay/ Liaison XL

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
82653   1    

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
82653   1    

Ordering Applications

Ordering Application Description
Cerner Pancreatic Elastase, Fecal