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HelpTest Code PANORSO Panorama Prenatal Panel
Useful For
Panorama is a blood-based genetic, prenatal screening test of the pregnant mom that screens for common chromosomal conditions that affect a baby's health.
Synonyms/Keywords
Trisomy 21, Trisomy 18, Trisomy 13, Monosomy X, Triploidy, 22q11.2 Deletion, Chromosome abnormalities, Down Syndrome, Edwards Syndrome, Patau Syndrome, Turner Syndrome, Klinefelter Syndrome, Triple X Syndrome, Jacob's Syndrome
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Specimen Volume |
Specimen Minimum Volume |
|---|---|---|---|---|
| No | Whole Blood |
Panorama Collection Kit Refer to the collection Kit and follow the collection and mailing instructions provided in the kit, as well as the Collection Processing Instructions (below). |
10 mL in each of two DNA Streck tubes | 8 mL in each of two DNA Streck tubes |
Collection/Processing Instructions
Collect the whole blood specimen using a 21 gauge straight needle, NOT a butterfly, as the use of butterfly needles can result in a need to redraw the specimen. Completely fill TWO 10 mL cell free DNA Streck tubes supplied in the collection kit. Allow 60-90 seconds for each tube to fill. Vein collapse may require second venipuncture with a fresh tube.
Gently invert each tube at least 10 times immediately after it is filled. Do not shake the tube(s) vigorously. Do not seal tubes with paraffin film. DO NOT REFRIGERATE OR FREEZE sample at any time. Store and transport specimen tubes at ambient temperature (43-98 F or 6-37 C).
Specimen Stability Information
Store and transport specimen tubes at ambienttemperature (43-98 F or 6-37 C).
| Specimen Type | Temperature | Time |
| Whole Blood | Ambient | 7 days |
Rejection Criteria
Refrigerated specimen
Frozen specimen
Test Information
The Panorama Prenatal Panel is able to determine the likelihood that the pregnancy could be affected with chromosome abnormalities including Down syndrome (trisomy 21), trisomy 18, trisomy 13, monosomy X and triploidy; and 22q11.2 deletion. While it is not the sole purpose of the test, the sex of the baby can also be screened for using Panorama.
Interpretations
An interpretive report will be provided.
Panorama is a screening test, which means that Panorama does not make a final diagnosis. A high-risk Panorama result means that a pregnancy could be affected by the condition that has screened positive. However, it cannot be known for sure if a baby has that condition based upon screening results alone. All medical decisions should be made after discussion with a heathcare provider regarding diagnostic testing during the pregnancy, like amniocentesis or chorionic villus sampling (CVS), or testing the baby after delivery.
Reference Range Information
An interpretive report will be provided
Performing Laboratory Name
Natera, Inc.
Referral Laboratory Information
| Address | Telephone | Website Link | Marshfield Lab Account # |
|---|---|---|---|
|
201 Industrial Road Suite 410 San Carlos, CA 94070-2396 |
650-249-9090 |
Note: Natera also performs testing in Austin, Texas. Samples will be sent to either California or Texas, depending on what address is listed on the prepaid address label provided by Natera.
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Natera, Inc. | Monday through Sunday | 3-6 Weeks | SNP (single nucleotide polymorphism) based NIPT (Non-invasive prenatal testing). |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 81420 | 1 | Fetal chromosomal aneuploidy genomic sequence analysis panel, circulating cell-free fetal DNA in maternal blood, must include analysis of chromosomes 13, 18 and 21. |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 81420 | 1 | Fetal chromosomal aneuploidy genomic sequence analysis panel, circulating cell-free fetal DNA in maternal blood, must include analysis of chromosomes 13, 18 and 21. |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Panorama Prenatal Panel |