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HelpTest Code PROLAC Prolactin
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Plasma/Serum | Lithium Heparin Plasma Separator Tube (PST) | Lithium Heparin Green Top (GTT), Serum Separator Tube (SST), Red Top Tube (RTT) | 1.0mL | 0.5 mL | 0.3 mL |
Collection/Processing Instructions
Samples collected in a RTT must be removed from the clot within 1 hour for storage or transport.
Samples collected in SST or PST must be removed from the primary tube within 4 hours for transport.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum/Plasma | Ambient | 8 hours |
| Refrigerated | 2 days | |
| Frozen | > 2 days |
Rejection Criteria
Gross Hemolysis
Moderate Icterus
Interferences
Human Anti-Murine Antibodies (HAMA) may develop leading to test interference in patients receiving murine-based agents for chemotherapy or tumor-imaging studies.
Interpretations
Highest levels are seen in the morning 3-4 hours after awakening with levels decreasing 20-40% later in the afternoon. Elevations are seen in pregnancy and postpartum lactation as well as with physical exercise and stress. Large (5-10 fold) increases are usually associated with a prolactin-secreting tumor.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield |
Female: Premenopausal: 3.3-23.7 ng/mL Postmenopausal: 2.7-19.6 ng/mL
Male: 2.6-13.1 ng/mL |
Marshfield Labs Performing Department
Marshfield Labs Chemistry
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | Less than 2 hours | Immunoenzymatic assay/ Beckman Coulter Unicel DXI |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 84146 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 84146 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Prolactin Level |