Test Code PROT-SM Protein S Antigen, On Coumadin (500530)
Additional Codes
LabCorp Test Code: 500530
Synonyms/Keywords
Protein S Antigen, Protein S Antigen/Factor VII Antigen Ratio
Specimen Requirements
| Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume | Pediatric Minimum Volume |
|---|---|---|---|---|---|
| Platelet poor plasma | Citrated Blue Top Tube (BTT) | 2 mL | 1 mL |
Collection/Processing Instructions
- Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.
- The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood.
- Centrifuge and carefully remove the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a transfer tube.
- Freeze immediately and maintain frozen until tested.
To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested. If feasible, it is strongly recommended that patients be tested for Free Protein S Antigen while OFF warfarin (coumadin) for at least two weeks.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma |
Freeze at -70 deg C. (preferable at -70 deg C, but -20 deg C is acceptable for outreach). |
60 days |
Rejection Criteria
|
Gross Hemolysis |
|---|
| Gross Lipemia |
| Thawed |
Test Components
Test includes Protein S antigen, Factor VII antigen, and Prot S/Factor VII ratio.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| LabCorp forwards to Esoterix | Indicated on report |
Performing Laboratory Name
LabCorp of America
Referral Laboratory Information
| Address | Telephone | Website Link | Marshfield Lab Account # |
|---|---|---|---|
|
6370 Wilcox Road Dublin, OH 43016 |
866-235-2291 | www.labcorp.com | 48300485 |
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| LabCorp forwards to Esoterix | Tuesday, Friday | 4-7 days | ELISA |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 85305 | 1 | Protein S, total | ||
| 85230 | 1 | Clotting Factor VII Proconvertin Stable Factor |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 85305 | 1 | Protein S, total | ||
| 85230 | 1 | Clotting Factor VII Proconvertin Stable Factor |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Protein S Antigen-ON Coumadin (500530) |