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Test Code PROT-SM Protein S Antigen, On Coumadin (500530)

Additional Codes

LabCorp Test Code: 500530

Synonyms/Keywords

Protein S Antigen, Protein S Antigen/Factor VII Antigen Ratio

Specimen Requirements

Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume Pediatric Minimum Volume
Platelet poor plasma Citrated Blue Top Tube (BTT)   2 mL 1 mL  

Collection/Processing Instructions

  1. Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio.
  2.  The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood.
  3. Centrifuge and carefully remove the plasma using a plastic transfer pipette, being careful not to disturb the cells. Transfer the plasma into a transfer tube. 
  4. Freeze immediately and maintain frozen until tested.

To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested. If feasible, it is strongly recommended that patients be tested for Free Protein S Antigen while OFF warfarin (coumadin) for at least two weeks. 

Specimen Stability Information

Specimen Type Temperature Time
Plasma

Freeze at -70 deg C.

(preferable at -70 deg C, but -20 deg C is acceptable for outreach).

60 days

Rejection Criteria

Gross Hemolysis

Gross Lipemia
Thawed

Test Components

Test includes Protein S antigen, Factor VII antigen, and Prot S/Factor VII ratio.

Reference Range Information

Performing Location Reference Range
LabCorp forwards to Esoterix Indicated on report

Performing Laboratory Name

LabCorp of America

Referral Laboratory Information

Address Telephone Website Link Marshfield Lab Account #

6370 Wilcox Road

Dublin, OH 43016

866-235-2291 www.labcorp.com 48300485

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
LabCorp forwards to Esoterix Tuesday, Friday 4-7 days ELISA

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
85305   1 Protein S, total  
85230   1 Clotting Factor VII Proconvertin Stable Factor  

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
85305   1 Protein S, total  
85230   1 Clotting Factor VII Proconvertin Stable Factor  

Ordering Applications

Ordering Application Description
Cerner Protein S Antigen-ON Coumadin (500530)