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Test Code PYRCSO Pyruvate, Spinal Fluid

Additional Codes

Mayo Test Code: PYRC

Reporting Name

Pyruvic Acid, CSF

Useful For

Investigating possible disorders of mitochondrial metabolism, when used in conjunction with cerebrospinal fluid lactate, collected at the same time, to determine the lactate-to-pyruvate (L:P) ratio

 

Evaluating patients with neurologic dysfunction and normal blood L:P ratios

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

CSF


Additional Testing Requirements


This test does not calculate the lactate:pyruvate ratio. To obtain this information, both this test and LASF1 / Lactic Acid, Spinal Fluid must be ordered. The ratio can be calculated from the results obtained from these tests.



Specimen Required


Specimen Type: Spinal fluid

Container/Tube: Sterile vial

Specimen Volume: 0.6 mL

Collection Instructions: Send specimen from vial 4.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 7 days
  Frozen  14 days
  Ambient  7 days

Reference Values

0.06-0.19 mmol/L

Day(s) Performed

Monday, Thursday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

84210

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PYRC Pyruvic Acid, CSF 14122-6

 

Result ID Test Result Name Result LOINC Value
83356 Pyruvic Acid, CSF 14122-6

Cautions

Correct specimen collection and handling is crucial to achieve reliable results.

 

Pyruvic acid levels alone have little clinical utility. Abnormal concentrations of pyruvic acid and lactate-to-pyruvate (L:P) ratios are not diagnostic for a particular disorder but must be interpreted in the context of the patient's clinical presentation and other laboratory studies.

 

For the L:P ratio, both analytes should be determined using the same specimen.

 

When comparing blood and cerebrospinal fluid (CSF) L:P ratios, blood and CSF specimens should be collected at the same time.

Report Available

2 to 5 days

Specimen Retention Time

2 months

Reject Due To

Gross hemolysis Reject

Method Name

Spectrophotometry (SP)