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Test Code QHV6PSO Human Herpesvirus-6 A and B DNA Detection and Quantification, PCR, Plasma

Additional Codes

Mayo Test Code: QHV6P


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube:

Preferred: Plastic vial

Acceptable: Screw-capped, sterile container

Specimen Volume: 1 mL Plasma

Collection Instructions: Centrifuge and aliquot plasma into a plastic vial.


Useful For

As an adjunct in the rapid diagnosis of human herpesvirus-6 infection using plasma specimens

 

This test should not be used to screen asymptomatic patients

Method Name

Real-Time Polymerase Chain Reaction (PCR)

Reporting Name

HHV-6 A and B DNA Quant PCR, P

Specimen Type

Plasma EDTA

Specimen Minimum Volume

Plasma: 0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Refrigerated (preferred) 7 days
  Frozen  7 days
  Ambient  24 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Heparin Reject

Reference Values

Undetected

Cautions

The sensitivity of the assay is dependent upon the quality of the specimen submitted.

 

A negative result does not exclude human herpesvirus-6 (HHV-6) infection. Therefore, the results obtained should be used in conjunction with clinical findings to make an accurate diagnosis.

 

This assay detects nucleic acid and, therefore, cannot distinguish between replicating and nonreplicating virus (ie, remnant viral nucleic acid). Test performance depends on the viral load in the specimen and may not correlate with cell culture performed on the same specimen.

 

Although this assay may detect dual infections of HHV-6A and HHV-6B, low level infections may be masked when in the presence of a higher concentration of an HHV-6 subtype.

 

Viral loads may vary between laboratory-developed assays. When monitoring a patient’s HHV-6 viral load, the same method and sample type should be used.

 

This test cannot be converted to IU/mL. It is recommended to utilize the same test for the duration of the clinical care for consistency in reporting units (copies/mL).

Day(s) Performed

Monday through Friday

Report Available

1 to 5 days

Specimen Retention Time

7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

87533

LOINC Code Information

Test ID Test Order Name Order LOINC Value
QHV6P HHV-6 A and B DNA Quant PCR, P 49392-4

 

Result ID Test Result Name Result LOINC Value
622169 HHV6 A DNA Detect/Quant, P 49392-4
622170 HHV6 B DNA Detect/Quant, P 49392-4

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Kidney Transplant Test Request

-Microbiology Test Request (T244)