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Test Code SCT Silica Clotting Time (SCT)

Synonyms/Keywords

PTT-LA, Lupus Anticoagulant PTT

Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No *Platelet Poor Citrated Plasma Citrated Blue Top Tube (BTT)   0.75 mL 0.75 mL 0.5 mL

Collection/Processing Instructions

One 0.75 mL citrated Blue Top Tube (BTT) plasma aliquot.  (If more than one coagulation test is ordered, a separate aliquot is needed for each test.)

  • Collect in Citrated Blue Top Tube (BTT)
  • Citrate anticoagulant must be adjusted for HCT >55%
  • Tube must be at least 90% full
  • Invert completely 3-4 times (without shaking) to mix

*See Instructions for:  Preparation of Platelet Poor Plasma

Specimen Stability Information

Specimen Type Temperature Time
Plasma Room Temp 4 hours
Refrigerated 4 hours
Frozen (-70) 6 months

Rejection Criteria

Clotted or Hemolyzed sample

Contamination with IV or Hickman Line fluids

Specimens that thaw during storage or transport

Test Components

SCT ratio

Test Information

To increase the sensitivity and specificity of the laboratory diagnosis of lupus anticoagulants (LA) both the DRVVT and the SCT should be ordered.  These two tests have been combined as a Lupus Anticoagulant Panel (LAPAN) test order.

 

Lupus anticoagulant testing (DRVVT and SCT) should not be performed on patients receiving rivaroxaban, apixaban, dabigatran, or warfarin.  For patients on these medications, one may consider anticardiolipin antibody and/or anti-beta-2 glycoprotein 1 antibody testing.

 

See Lab Clinical Practice Guidlines: Hypercoagulability for more information 

Reference Range Information

SCT ratio:  ≤1.16 Negative for LA

SCT ratio:  >1.6 Positive for LA

Marshfield Labs Performing Department

Marshfield Labs Coagulation

Performing Information

Performing Location Day(s) Test Performed Analytical Time

Methodology/Instrumentation

Marshfield Monday, Wednesday, Friday Less than 2 hours ACL TOP 550

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
85732     Optical Clot Detection  

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
85732     Optical Clot Detection  

Ordering Applications

Ordering Application Description
Cerner Silica Clotting Time