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HelpTest Code SM Smith Antibodies
Useful For
Sm or Smith Antibody is considered a marker for SLE. It occurs in a minority of SLE patients with a low sensitivity.
Synonyms/Keywords
SM, ENA, Extractable Nuclear Antibodies, Smith Antibody
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) or Serum Separator Tube (SST) | 1.0 mL | 0.4 mL | 0.3 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated | 7 days |
| Frozen | >7 days |
Rejection Criteria
| Gross Lipemia |
| Gross Hemolysis |
| Heat inactivated samples |
Test Components
Sm (Smith) Antibodies
Interpretations
Positive results supports diagnosis of SLE with renal involvement.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield |
Negative <1.0 AI Analytical measuring range is 0.2-8.0 AI (Antibody Index) |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Flow Immunassay / Bio-Rad BioPlex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86235 | 1 | Antibody to extractable nuclear antigen |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86235 | 1 | Antibody to extractable nuclear antigen |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Smith Antibodies |