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HelpTest Code SSASSB Sjogrens Antibodies, SSA and SSB
Useful For
A confirmatory test for the evaluation of patients with signs and symptoms of Sjogren’s syndrome and other connective tissue diseases. SSA/Ro and SSB/La antibodies occur in SLE and Sjogren’s syndrome.
Synonyms/Keywords
SSA and SSB, Ro and La, Extractable Nuclear Antigen, ENA
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) or Serum Separator Tube (SST) | 1.0 mL | 0.4 mL | 0.3 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
| Gross lipemia | |
|---|---|
| Gross hemolysis | |
| Heat inactivated samples |
Interpretations
A positive result supports the diagnosis of Sjogren's syndrome or other connective tissue diseases.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | Negative: <1.0 |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86235 | 2 | Extractable nuclear antigen |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86235 | 2 | Extractable nuclear antigen |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Centricity | Sjogrens Antibodies |
| Cerner | Sjogren's Antibodies, SSA and SSB |