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HelpTest Code SYPHOR Syphilis Confirmation by RPR/TP-PA
Useful For
Order this test if the patient has a positive antibody screen (IgG or IgM). The RPR will be performed. In case the results of the antibody testing disagree with the RPR, another treponemal test, Treponemal pallidum Particle Agglutination (TPPA) will be performed at an additional charge.
NOTE: The CDC and WHO recommend both a positive antibody test against the causative agent Treponema pallidum and a positive non-treponemal test such as the Rapid Plasma Reagin (RPR) before making a serological diagnosis of syphilis.
Synonyms/Keywords
Syphilis Screen, Rapid Plasma Reagin (RPR), Treponemal pallidum Particle Agglutination (TP-PA), VDRL
Specimen Requirements
| Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|
| Serum | Red Top Tube (RTT) or Serum Separator Tube (SST) | 1.0 mL | 0.5 mL | 0.5 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
Gross hemolysis
Test Components
Syphilis Treponemal IgG Antibody Screen, Rapid Plasma Reagin (RPR) (if needed), Treponemal pallidum Particle Agglutination (TP-PA) (if needed)
Interpretations
Link to: Syphilis Testing Algorithm
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | Negative |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Mulitplex Flow Immunoassay/ BioRad Bioplex 2200 OR RPR (Rapid Plasma Reagin) Flocculation Test |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86593 | 1 | RPR | ||
| 86780 | 1 | TP-PA (if needed) |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86593 | 1 | RPR | ||
| 86780 | 1 | TP-PA (if needed) |
Ordering Applications
| Ordering Application | Description |
|---|---|
| COM | Syphilis Confirmation by RPR/TP-PA |