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HelpTest Code TA-TG Thyroglobulin Antibody
Useful For
This test is used to rule out potentially unreliable Thyroglobulin (Tg) results due to interference (endogenous Anti-thyroglobulin antibodies) in the follow-up of patients with differentiated thyroid carcinoma.
Synonyms/Keywords
Thyroglobulin (Tg) Antibody, Anti-Thyroglobulin Antibody, Anti-TG
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 1.0 mL | 0.4 mL | 0.3 mL |
Collection/Processing Instructions
High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay. It is recommended that patients refrain from consuming any multivitamin or supplement containing biotin for at least 72 hours prior to collection of a blood sample.
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | 6 months |
Rejection Criteria
Serum not separated from cells within 2 hours
Test Information
Anti-Tg values determined by different methods vary significantly and cannot be compared. Patients should be followed by using the same methods. Comparing anti-Tg values from different methods might lead to erroneous clinical interpretations.
For routine screening of auto-immune thyroid disease, anti-thyroid peroxidase antibody (Anti-TPO) is recommended.
The drug asfotase alfa (STRENSIQ), a recombinant form of alkaline phosphatase, is expected to interfere with in vitro diagnostic assays utilizing an alkaline phosphatase detection system. Test samples from patients taking asfotase alfa with a non-alkaline phosphatase methodology.
Interferences
High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | ≤ 40 IU/mL (Applicable to all age groups) |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Chemiluminescent Immunoassay (Siemens, Immulite 2000)/ Immulite 2000 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86800 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86800 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Thyroglobulin Antibody |