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Test Code TRAM Tramadol Quantitation, Urine

Useful For

Detecting exposure to tramadol to monitor compliance in taking prescribed medications or to detect abuse. 

Synonyms/Keywords

Ultracet, Ultram

Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No Urine Sage urine collection container Sterile plastic container with no preservatives 2 mL 1 mL 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Ambient 72 hours
Refrigerate (Preferred) 30 days

Test Information

This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.


This test will confirm quantitatively for Tramadol, a dual action analgesics. It is a mu-opioid receptor agonist and a weak inhibitor of norepinephrine and serotonin reuptake. Tramadol is used for managing moderate to severe chronic pain and is habit forming.

Reference Range Information

Performing Location Reference Range
Marshfield Negative.  Positives are reported with a quantitative LCMS/MS result.

Marshfield Labs Performing Department

Marshfield Labs Special Chemistry

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield Monday through Friday 2-4 days Liquid Chromatography/Tandem Mass Spectrometry (LCMS/MS) using Multiple Reaction Monitoring

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
80373   1 Tramadol Confirmation  
G0480   1 Tramadol Confirmation For Marshfield Clinic and Medicare/Medicaid

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
80373   1 Tramadol Confirmation  
G0480   1 Tramadol Confirmation For Medicare/Medicaid

Ordering Applications

Ordering Application Description
Cerner Tramadol Quantitation, Urine
COM Tramadol, Urine