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HelpTest Code TTG-IGA Tissue Transglutaminase IgA Antibody
Useful For
Tissue Transglutaminase antibodies are useful in the diagnosis of gluten sensitive enteropathy (celiac disease). At present, tTG IgA is the most useful screening test for celiac disease. Levels of antibody decline after the patient maintains a gluten free diet.
Synonyms/Keywords
Sprue, Celiac, tTG IgASpecimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 1.0 mL | 1.0 mL | 0.5 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
| Gross lipemia |
|---|
| Gross hemolysis |
| Heat inactivated samples |
| Gross icterus |
Test Components
Tissue Transglutaminase IgA Antibodies
Test Information
Tissue Transglutaminase antibodies are useful in the diagnosis of gluten sensitive enteropathy (celiac disease). At present, tTG IgA is the most useful screening test for celiac disease. Levels of antibody decline after the patient maintains a gluten free diet.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield |
Negative <15.0 U/mL |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Flow Immunoassay/ BioRad Bioplex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86364 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86364 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Tissue Transglutaminase Antibody IgA |