Test Code TTG-IGG Tissue Transglutaminase IgG Antibody
Useful For
An aid in the diagnosis of gluten sensitive enteropathy (celiac disease), in tTG IgA antibody negative patients with confirmed IgA deficiency.
Synonyms/Keywords
Sprue, Celiac, tTGSpecimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 1.0 mL | 0.5 mL | 0.5 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
| Gross lipemia | |
|---|---|
| Gross hemolysis | |
| Heat inactivated samples |
|
| Gross icterus |
Test Components
Tissue Transglutaminase IgG Antibodies
Test Information
Patients with celiac disease produce anti-tissue transglutaminase antibodies of the IgA isotype. This test is recommended for patients with low serum IgA levels where the production of IgA antibodies may be impaired.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | Negative < 15.0 U/mL |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Flow Immunoassay/ BioRad Bioplex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86364 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86364 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner |
Tissue Transglutaminase IgG Antibody |