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Test Code TTG-IGG Tissue Transglutaminase IgG Antibody

Useful For

An aid in the diagnosis of gluten sensitive enteropathy (celiac disease), in tTG IgA antibody negative patients with confirmed IgA deficiency.

Synonyms/Keywords

Sprue, Celiac, tTG

Specimen Requirements

Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No Serum Red Top Tube (RTT) Serum Separator Tube (SST) 1.0 mL 0.5 mL 0.5 mL

Collection/Processing Instructions

Separate serum from cells within 2 hours of collection.

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerate 7 days
Frozen > 7 days

Rejection Criteria

Gross lipemia
Gross hemolysis
Heat inactivated samples
Gross icterus

Test Components

Tissue Transglutaminase IgG Antibodies

Test Information

Patients with celiac disease produce anti-tissue transglutaminase antibodies of the IgA isotype. This test is recommended for patients with low serum IgA levels where the production of IgA antibodies may be impaired.

Reference Range Information

Performing Location Reference Range
Marshfield Negative < 15.0 U/mL

Marshfield Labs Performing Department

Marshfield Labs Immunodiagnostics

Performing Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield Monday through Friday 1 day Multiplex Flow Immunoassay/ BioRad Bioplex 2200

CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
86364

Outreach CPT Codes

CPT Modifier
(if needed)
Quantity Description Comments
86364

Ordering Applications

Ordering Application Description

Cerner
Tissue Transglutaminase IgG Antibody