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HelpTest Code TTGAB Tissue Transglutaminase AB, IgA and IgG
Useful For
Tissue Transglutaminase antibodies are useful in the diagnosis of gluten-sensitive enteropathy (Celiac disease). The tTG-IgG assay may aid in the diagnosis of gluten sensitive enteropathy in tTG-IgA negative patients with confirmed IgA deficiency. A negative Tissue Transglutaminase antibody test alone does not rule out gluten-sensitive enteropathy.
Synonyms/Keywords
tTG Ab, celiac disease, sprue
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) or Serum Separator Tube (SST) | 1.0 mL | 1.0 mL | 0.5 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
| Gross lipemia | |
|---|---|
| Gross hemolysis | |
| Heat inactivated samples | |
| Gross icterus |
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | IgG: < 15.0 U/mL: Negative |
| IgA: < 15.0 U/mL: Negative |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Mulitplex Flow Immunoassay -BioRad Bioplex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86364 | 2 | tTG IgG and tTG IgA |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86364 | 2 | tTG IgG and tTG IgA |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Tissue Transglutaminase Antibody IgA and IgG |