Test Code UBILALSO Bile Alcohols, Urine
Additional Codes
Sent to Oregon Health & Science University
Synonyms/Keywords
URINARY BILE ALCOHOL 5b-CHOLESTANE-3a,7a,12a,23S,25-PENTOL, TOTAL
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| Random Urine | Urine Tube | 10.0 mL | 2.0 mL |
Collection/Processing Instructions
No preservative
Lab: Use "Oregon Health & Science" requisition (Sterol Analysis Lab) found in Limited Use Requisitions folder.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Urine | Frozen (preferred) | Long Term |
| Ambient | 5 Days | |
| Refrigerated | 11 Days |
Reference Range Information
| Performing Location | Reference Range |
| Oregon Health & Science University |
Normal concentration in unaffected individuals, n=20 < 200 ng/mL Concentration in CTX-affected untreated individuals, (n=8) 67,322 ± 39,087 ng/mL [20,022-118,411] mean ± SD [range] |
Performing Laboratory Name
Oregon Health & Science University
Referral Laboratory Information
| Address | Telephone | Website Link |
|---|---|---|
|
Attn: Andrea DeBarber Physiology & Pharmacology Department (L334) RJH Room 3360, Dock 4 Oregon Health & Science University 3181 SW Sam Jackson Park Road Portland, OR 97239-3098 |
503-494-4593 | https://www.ohsu.edu/ |
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Oregon Health & Science University | Batched Testing | 2-4 Weeks | Addition of 23S-pentol-d6 method internal standard followed by incubation of urine with -glucuronidase enzyme. Isotope-dilution quantification performed using positive-mode LC-ESI-MS/MS multiple reaction monitoring of 23S-pentol (m/z 453.3>361.4) and internal standard (m/z 459.3>343.5) with a reversed-phase gradient utilizing a 4.6x50mm Biphenyl (2.6 m) column. Linear up to 5,000 ng/mL without dilution. No significant interference from common over the counter and prescription medications. Carry over response in blanks is < 1% of the LLOQ for the analyte and < 0.5% for the internal standard. |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82542 | 1 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82542 | 1 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Bile Alcohols, Urine |