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HelpTest Code UCASSO Unity Aneuploidy Screen
Useful For
Assessing fetal risk for chromosomal conditions:Trisomy 21, 18, 13; Sex chromosome aneuploidy; Zygosity determination included for twin pregnancies. Optional: Fetal sex, fetal RhD for RdD-negative pregnant patients, fetal antigen reporting for alloimmunized patients, 22q11.2 microdeletion
Specimen Requirements
| Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
|---|---|---|---|---|
| Whole Blood | 3- Streck 10 mL tubes | 30 mL total: 10 mL in each of the three DNA Streck tubes | 20 mL |
Collection/Processing Instructions
Provider will give patient a test kit and completed requisition form. Patient will present in phlebotomy for blood draw with the kit and requisition form.
Collect the whole blood specimen using a 21 gauge straight needle, NOT a butterfly, as the use of butterfly needles can result in a need to redraw the specimen. Completely fill THREE 10 mL cell free DNA Streck tubes supplied in the collection kit. Allow 60-90 seconds for each tube to fill. Vein collapse may require second venipuncture with a fresh tube.
Gently invert each tube at least 10 times immediately after it is filled. Do not shake the tube(s) vigorously. Do not seal tubes with paraffin film. DO NOT REFRIGERATE OR FREEZE sample at any time. Store and transport specimen tubes at ambient temperature (43-98 F or 6-37 C) with the kit-provided temperature-regulating pack.
Send tubes and requisition form in kit box to Marshfield Labs Specimen Processing for packaging and shipping.
NOTE: If this test is ordered together with the Unity Screen Carrier Screen with Reflex sgNIPT" test, only 3 Streck tubes are required in total (i.e. ordering both tests does not require a total of 6 Streck tubes).
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood | Ambient | 7 Days |
Rejection Criteria
Refrigerated or Frozen specimens
Performing Laboratory Name
BillionToOne
Referral Laboratory Information
| Address | Telephone | Website Link | Marshfield Lab Account # |
|---|---|---|---|
| 3200 Whipple Road Union City, CA 94587 |
605-460-2551 | https://billiontoone.com | 6542 |
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| BillionToOne | Monday- Friday | 7-10 days | Next Generation Sequencing: Counting and SNP-based methodologies, QCT technology |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 81420 | 1 | |||
| 81403 | As Needed | |||
| 81479 | As Needed | |||
| 81422 | As Needed |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Unity Aneuploidy Screen (UCASSO) |