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HelpTest Code VZI Varicella Zoster Virus (VZV) Immune Status
Useful For
This test qualitatively determines immune status for Varicella Zoster virus to in identifying nonimmune individuals for consideration of vaccination. The test does include the numerical "Antibody Index (AI)" result.
Synonyms/Keywords
Varicella-zoster Antibody, Chickenpox
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 1.0 mL | 0.5 mL | 0.5 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 7 days |
| Frozen | > 7 days |
Rejection Criteria
| Gross hemolysis |
|---|
| Gross lipemia |
| Gross icterus |
| Plasma |
| Heat inactivated sera |
Test Information
This test uses a multiplex flow fluorescence immunoassay to detect IgG-class antibodies directed against VZV.
Interpretations
Reported as Positive, Equivocal or Negative
Positive: AI ≥ 1.1, Equivocal: AI 0.9-1.0, Negative: AI ≤ 0.8
This test is to be used only to establish serological status to VZV. The reported AI value is for reference only.
A positive test result may be due to immunization or natural infection. A positive test has a high correlation with, but does not guarantee, immunity to VZV.
A negative test result indicates a lack of antibody to VZV marking the individual as a candidate for vaccination.
An equivocal result for this test indicates some reactivity of the individual's blood to the components of this test, but serological status cannot be determined. In such cases the patient may be retested once to detect sero-conversion; alternatively, vaccination may be considered.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield |
Negative |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Immnoassay/Biorad BioPlex 2200 |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86787 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86787 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Varicella Zoster Antibody IgG |