Test Code PathGYN - Liq Prep w/HPV Cytology, Pap, Liquid Prep w/HPV
Useful For
The cervicovaginal smear is a test for the detection of premalignant, cellular changes, which are precursors to carcinoma of the cervix. The conventional pap smear, when used as part of a regular screening program has been credited with reducing the incidence of cervical cancer worldwide.
The Thin-Prep pap test has been approved by the U.S. Food and Drug Administration as a replacement for the conventional pap smear and is endorsed by the College of American Pathologists as a method to improve the accuracy of pap examinations. The Thin Prep pap test improves detection of low-grade and more severe lesions. By improving detection, disease can be identified at an earlier stage when it is more easily and cost-effectively treated.
Synonyms/Keywords
Pap and HPV Co-Testing, Pathology GYN Request - Liquid Prep w/HPV
Specimen Requirements
| Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|
| ThinPrep vial | 20 mL |
Collection/Processing Instructions
Obtain an adequate sampling from the ectocervix using a plastic spatula. Immediately rinse the spatula into the ThinPrep PreservCyt Solution vial by swirling the spatula vigorously in the vial 10 times. Discard the spatula. Obtain an adequate sampling from the endocervix using an endocervical brush device. Insert the brush into the cervix until only the bottom-most fibers are exposed. Slowly rotate 1/4 to 1/2 turn in one direction. DO NOT OVER-ROTATE. Immediately rinse the brush in the PreservCyt Solution by rotating the device in the solution 10 times while pushing against the PreservCyt vial wall. Swirl the brush vigorously to further release material. Discard the brush. Tighten the cap so that the torque line on the cap passes the torque line on the vial.
Record the patient name and medical record number on the vial.
NOTE: Self-collected pap tests are not FDA approved and will be rejected by the laboratory.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| ThinPrep | Room Temperature |
4 weeks |
Test Information
For additional HPV information, see the Human Papillomavirus (HPV) test (available to outreach clients only).
This fulfills the 2012 ACOG Pap/HPV Co-Testing Guideline Recommendations.
Include specimen source, pertinent patient history and clinical information along with the appropriate ICD-10 code on the electronic order or test requisition form.
For Collection Techniques/Instructions see:
Endocervical Brush/Spatula Collection Guide
Cervical Broom Collection Guide
For list of a compatible lubricants and lubricant usage see:
ThinPrep Pap Test Lubricant Compatibility List
Lubricant Usage During Pap Collection Letter
For Appropriate ThinPrep Vial Labeling see:
ThinPrep Vial Labeling Instructions
Interferences
Lubricants may increase the risk of contaminating and obscuring the cellular sample. When collecting a specimen, warm water is suggested to lubricate and warm the speculum. If a lubricant must be utilized, a sparing application to the outer portion of the speculum, with avoidance of the tip, is recommended. The following lubricant brands are acceptable to use with the PreServCyt Solution: Surgilube, CerviLube or Pap Test Lubricating Jelly.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield - Cytopathology | Interpretative Report (Bethesda System) |
Marshfield Labs Performing Department
Marshfield Labs Cytopathology
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield - Cytology | Monday - Friday | 3 days | ThinPrep, Light Microscopy |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 88142 | ScreeningPurposes - ThinPrep Pap |
|
||
| 88141 | ScreeningPurposes - Interp. By Physician |
|
||
| 88142 | DiagnosticPurposes - ThinPrep Pap |
|
||
| 88141 | DiagnosticPurposes - Interp. By Physician |
|
||
| 87624 | HPV- Nucleic Acid Method |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 88142 | ScreeningPurposes - ThinPrep Pap |
|
||
| 88141 | ScreeningPurposes - Interp. By Physician |
|
||
| 88142 | DiagnosticPurposes - ThinPrep Pap |
|
||
| 88141 | DiagnosticPurposes - Interp. By Physician |
|
||
| 87624 | HPV- Nucleic Acid Method |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Pathology GYN Request - Liquid Prep w/HPV |