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HelpTest Code RPRNEO Syphilis, Neonatal Screen (less than 1 month of age)
Useful For
This test is useful for the evaluation of neonates < one month of age suspected of having congenital syphilis. Positive tests will be titered. Note: Positive tests will not be confirmed with a second treponemal test as recommended by the CDC for individuals over the age of one month. For the determination of syphilis serostatus in individuals > one month in age, order Syphilis Antibody IgG/IgM (SYPHAB)
Synonyms/Keywords
Syphilis, RPR
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) or Serum Separator Tube (SST) | 0.5 mL | 0.3 mL | 0.3 mL |
Collection/Processing Instructions
Separate serum from cells within 2 hours of collection.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 5 days |
| Frozen | > 5 days |
Rejection Criteria
| Gross hemolysis | |
|---|---|
| Gross lipemia |
Test Information
This semi-quantitative test is intended for testing neonates (<1 month of age) only. It does not include a confirmatory treponemal test as recommended by the CDC for individuals one month of age and above. Order Syphilis Antibody, IgG (SYPHAB) as the primary syphilis diagnostic test.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield | Negative |
Marshfield Labs Performing Department
Marshfield Labs Immunodiagnostics
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday | 1 day | Multiplex Flow Immunoassay/ Bio-Rad BioPlex 2200 OR RPR (Rapid Plasma Reagin) Flocculation Test |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86593 |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 86593 |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Syphilis, Neonatal Scr <1 month |