Home
HelpTest Code GAMPRIT Protein-Immunotyping (PEP,GAM,IT) and Beta 2 Microglobulin
Useful For
Quantitative immunoglobulins and protein electrophroresis are useful for detecting or monitoring monoclonal gammopathies and immune deficiencies. In inflammatory disorders such as Rheumatoid Arthritis, Lupus and Crohn’s Disease, and in lymphoproliferative disorders such as Multiple Myeloma and Chronic Lymphocytic Leukemia, serum B2 levels are frequently elevated, reflecting an increase rate of synthesis. Serum B2 levels have also been predictors of longevity in patients with Multiple Myeloma. Serum B2 levels may also be elevated due to renal insufficiency, and are useful in monitoring patients who have undergone renal transplants.
Synonyms/Keywords
Gammopathy profile, Monoclonal gammopathy profile, IF-B2 panel, Quantitative immunoglobulins in serum (IgG, IgA and IgM) with serum protein electrophoresis and Beta-2 Microglobulin
Specimen Requirements
| Fasting Required | Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
Pediatric Minimum Volume (no repeat) |
|---|---|---|---|---|---|---|
| No | Serum | Red Top Tube (RTT) | Serum Separator Tube (SST) | 2 mL | 1.5 mL | 1 mL |
Collection/Processing Instructions
Separate serum/plasma from cells within 2 hours of collection.
Please make 3 aliquots of serum for this test panel.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerate | 10 days |
Rejection Criteria
Plasma Samples
Test Components
IgG, IgA, IgM, Protein electrophoresis (Total Protein, Albumin, Alpha-1, Alpha-2, Beta and Gamma fractions), Beta-2 Microglobulin and total serum protein. Immunotyping may be ordered by interpreter, at an additional charge.
Test Information
Includes total serum protein, protein electrophoresis, immunoglobulin quantitation and beta-2 microglobulin quantitation. Phenotyping of heavy chains and light chains (kappa and lambda) may also be performed by Immunotyping electrophoresis for pathologist/PhD interpretation, and will be charged separately.
Reference Range Information
| Performing Location | Reference Range |
|
Marshfield |
Albumin: 3.70-4.90 g/dL Alpha-1 globulin: 0.20-0.40 g/dL Alpha-2 globulin: 0.50-0.90 g/dL Beta globulin: 0.60-1.00 g/dL Gamma globulin: 0.60-1.40 g/dL Beta-2 Microglobulin: 0.9-2.4 mg/L
Refer to link provided for Protein, Total Reference Ranges:
Referto link provided for Immunoglobulin Reference Ranges: |
Marshfield Labs Performing Department
Marshfield Labs Special Chemistry
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield | Monday through Friday |
6-8 hours If Immunotyping is required, an additional 24 hours is required. |
Immunoglobulins and Beta 2 Microglobulin: Turbidimetric method / The Binding Site, Optilite analyzer
Protein Electrophoresis: Capillary electrophoresis / Sebia Capillarys 2 protein system
Total serum protein: Biuret Blanked Endpoint Assay/Beckman AU
Immunotyping: Electrophoresis/Sebia Capillarys 2 Protein System |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82784 | 3 | IgG, IgA and IgM | ||
| 84165 | Protein electrophoresis | |||
| 82232 | Beta-2 Microglobulin | |||
| 86334 | Immunotyping (If needed) |
|
||
| 84155 | Total serum protein |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 82784 | 3 | IgG, IgA and IgM | ||
| 84165 | Protein electrophoresis | |||
| 82232 | Beta-2 Microglobulin | |||
| 86334 | Immunotyping (If needed) |
|
||
| 84155 | Total serum protein |
Ordering Applications
| Ordering Application | Description |
|---|---|
| Cerner | Protein-Immunotyping (PEP, GAM, IT) and Beta 2 Microglobulin |