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HelpTest Code Path GYN, Liq Prep Rflx ASCUS+&Geno Cytology, Pap, Liquid Prep w/HPV if ASCUS Plus + HPV Genotyping Reflex
Useful For
The cervicovaginal smear is a test for the detectionof premalignant, cellular changes, which are precursors to carcinoma of thecervix. The conventional pap smear, when used as part of a regular screening program has been credited with reducing the incidence of cervical cancer worldwide.
The Thin-Prep pap test has been approved by the U.S. Food and DrugAdministration as a replacement for the conventional pap smear and is endorsedby the College of American Pathologists as a method to improve the accuracy ofpap examinations. The Thin Prep pap test improves detection oflow-grade and more severe lesions. By improving detection, disease can beidentified at an earlier stage when it is more easily and cost-effectively treated.
Synonyms/Keywords
Pathology GYN Request – Liquid Prep Reflex ASCUS+ +Geno
Specimen Requirements
| Specimen Type | Preferred Container/Tube | Acceptable Container/Tube | Specimen Volume | Specimen Minimum Volume (allows for 1 repeat) |
|---|---|---|---|---|
| ThinPrep Vial | 20 mL |
Collection/Processing Instructions
Obtain an adequate sampling from the ectocervix using a plastic spatula. Immediately rinse the spatula into the ThinPrep PreservCyt Solution vial by swirling the spatula vigorously in the vial 10 times. Discard the spatula. Obtain an adequate sampling from the endocervix using an endocervical brush device. Insert the brush into the cervix until only the bottom-most fibers are exposed. Slowly rotate 1/4 to 1/2 turn in one direction. DO NOT OVER-ROTATE. Immediately rinse the brush in the PreservCyt Solution by rotating the device in the solution 10 times while pushing against the PreservCyt vial wall. Swirl the brush vigorously to further release material. Discard the brush. Tighten the cap so that the torque line on the cap passes the torque line on the vial.
Record the patient name and medical record number on the vial.
HPV Orders: If ThinPrep Pap and HPV if ASCUS or Higher is requested in the original order, the PreservCyt ThinPrep vial will be processed as a pap first and then the HPV test will be tested by the Molecular Pathology Department if the Pap Interpretation is : Atypical Squamous Cells of Undetermined Significance (ASC-US), Atypical Squamous Cells Cannot Exclude High Grade Squamous Intraepithelial Lesion (ASC-H), Low Grade Squamous Intraepithelial Lesion (LSIL), High Grade Squamous Intraepithelial Lesion (HSIL), Favor Neoplastic or Malignant Cells Present.
NOTE: Self-collected pap tests are not FDA approved and will be rejected by the laboratory.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| ThinPrep | Ambient | 4 weeks |
Test Information
For additional HPV information, see the Human Papillomavirus (HPV).
For additional HPV Genotyping information, see HPV-Human Papillomavirus Genotyping 16,18/45(NAM).
Include specimen source, pertinent patient history and clinical information along with the appropriate ICD-10 code on the electronic order or test requisition form.
For Collection Techniques/Instructions see:
For list of a compatible lubricants and lubricant usage see:
For Appropriate ThinPrep Vial Labeling see:
Interferences
Lubricants may increase the risk of contaminating andobscuring the cellular sample. When collecting a specimen, warm water issuggested to lubricate and warm the speculum. If a lubricant must be utilized,a sparing application to the outer portion of the speculum, with avoidance ofthe tip, is recommended. The following lubricant brands are acceptable to usewith the PreServCyt Solution: Surgilube, CerviLube or Pap Test Lubricating Jelly.
Reference Range Information
| Performing Location | Reference Range |
|---|---|
| Marshfield-Cytopathology | Interpretative Report (Bethesda System) |
Marshfield Labs Performing Department
Marshfield Labs Cytopathology
Performing Information
| Performing Location | Day(s) Test Performed | Analytical Time | Methodology/Instrumentation |
|---|---|---|---|
| Marshfield-Cytopathology | Monday-Friday | 3 days | ThinPrep/ Light Microscopy |
CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 88142 | Screening Purposes - ThinPrep Pap | |||
| 88141 | Screening Purposes - Interp. By Physician | |||
| 88142 | Diagnostic Purposes - ThinPrep Pap | |||
| 88141 | Diagnostic Purposes - Interp. By Physician | |||
| 87624 | HPV - Hybrid Capture Method, if needed | |||
| 87625 | HPV Genotyping (16, 18/45)(NAM) |
Outreach CPT Codes
| CPT | Modifier (if needed) |
Quantity | Description | Comments |
|---|---|---|---|---|
| 88142 | Screening Purposes - ThinPrep Pap | |||
| 88141 | Screening Purposes - Interp. By Physician | |||
| 88142 | Diagnostic Purposes - ThinPrep Pap | |||
| 88141 | Diagnostic Purposes - Interp. By Physician | |||
| 87624 | HPV - Hybrid Capture Method, if needed | |||
| 87625 | HPV Genotyping (16, 18/45) (NAM) |